Das Leibniz-Institut zur Analyse des Biodiversitätswandels

ist ein Forschungsmuseum der Leibniz Gemeinschaft

The role of ubiquitin ligase APC/C in regulating the meiotic cell cycle

Termin: 
Mo, 20.05.2019 - 17:15 Uhr
Treffpunkt: 
Poppelsdorfer Schloss
Ort: 
Hörsaal
Veranstaltungsart: 
Vortrag
Veranstaltungsreihe: 
Biologisches/Evolutionsbiologisches Kolloquium
Zielgruppe: 
Studierende
Vortragende / Vortragender: 
Prof. Dr. Thomas U. Mayer, Universität Konstanz

The meiotic cell cycle is unique in that it involves two M phases with no intervening S phase. A peculiar characteristic of female meiosis in vertebrates is that oocytes undergo distinct cell cycle arrests: immature oocytes arrest at prophase at meiosis I and following meiotic maturation they arrest as mature oocytes again at metaphase of meiosis II.

The prophase I arrest of immature oocytes – which belongs to the longest known cell cycle arrests – is released by hormonal stimulation, while the MII arrest of mature oocytes is released by fertilization.

Our research aims at a better understanding of how the interplay of reversible protein phosphorylation and selective destruction by the ubiquitin-proteasome pathway controls the MI and MII arrest of oocytes and the release of oocytes from these arrest stages.

Ansprechpartnerin / Ansprechpartner

Sektionsleiterin
+49 228 9122-241
+49 228 9122-295
h.waegele [at] leibniz-zfmk.de

Biologisches Kolloquium

Prof. Dr. A. Blanke
Institut für Evolutionsbiologie und Ökologie
An der Immenburg 1, 53121 Bonn

 

Prof. Dr. A. Suh
Leibniz-Institut zur Analyse des Biodiversitätswandels, Museum Koenig Bonn
Adenauerallee 160, 53113 Bonn

 

Ort: Großer Hörsaal, Poppelsdorfer Schloß oder online via ZOOM

Zeit: montags, 17.15 Uhr