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Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus

AutorInnen: 
Mock et al.
Erscheinungsjahr: 
2017
Vollständiger Titel: 
Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus
Autor/-innen des ZFMK: 
Publiziert in: 
Nature
Publikationstyp: 
Zeitschriftenaufsatz
DOI Name: 
doi:10.1038/nature20803
Keywords: 
Molecular evolution,Genome evolution
Bibliographische Angaben: 
Mock, T., Otillar, R.P., Strauss, J., McMullan, M., Paajanen, P., Schmutz, J., Salamov, A., Sanges, R., Toseland, A., Ward, B.J., Allen, A.E., Dupont, C.L., Frickenhaus, S., Maumus, F., Veluchamy, A., Wu, T., Barry, K.W., Falciatore, A., Ferrante, M.I., Fortunato, A.E., Glöckner, G., Gruber, A., Hipkin, R., Janech, M.G., Kroth, P.G., Leese, F., Lindquist, E.A., Lyon, B.R., Martin, J., Mayer, C., Parker, M., Quesneville, H., Raymond, J.A., Uhlig, C., Valas, R.E., Valentin, K.U., Worden, A.Z., Armbrust, E.V., Clark, M.D., Bowler, C., Green, B.R., Moulton, V., van Oosterhout, C., Grigoriev, I.V., 2017. Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus. Nature 541, 536–540. doi:10.1038/nature20803
Abstract: 

The Southern Ocean houses a diverse and productive community of organisms. Unicellular eukaryotic diatoms are the main primary producers in this environment, where photosynthesis is limited by low concentrations of dissolved iron and large seasonal fluctuations in light, temperature and the extent of sea ice. How diatoms have adapted to this extreme environment is largely unknown. Here we present insights into the genome evolution of a cold-adapted diatom from the Southern Ocean, Fragilariopsis cylindrus8, 9, based on a comparison with temperate diatoms. We find that approximately 24.7 per cent of the diploid F. cylindrus genome consists of genetic loci with alleles that are highly divergent (15.1 megabases of the total genome size of 61.1 megabases). These divergent alleles were differentially expressed across environmental conditions, including darkness, low iron, freezing, elevated temperature and increased CO2. Alleles with the largest ratio of non-synonymous to synonymous nucleotide substitutions also show the most pronounced condition-dependent expression, suggesting a correlation between diversifying selection and allelic differentiation. Divergent alleles may be involved in adaptation to environmental fluctuations in the Southern Ocean.